Choline is an essential nutrient that is related to the B vitamins. It is responsible for lipid (fat) metabolism and transport and has other jobs in the body related to cell membrane structure and other functions. Without choline, fats can become trapped in the liver and block metabolic functions. 

Lipotropic nutrients are most often combined with B12. B12, also called cobalamin, is a water-soluble vitamin that plays many key roles supporting normal function of the brain and nervous system, and is involved in the metabolism of every cell of the human body. B12 plays an important role in fatty acid metabolism and energy production.

Because most lipotropic injections include the ingredients listed above (methionine + inositol + choline), many providers refer to the shots as MIC injections. Many physicians using lipotropic injections or MIC injections such as lipo-mino or lipostat plus have found success by combining these treatments with an oral lipotropic tablet or spray to keep blood levels elevated between injections and accelerate the weight loss benefits.